UPBUpstream Bio, Inc.vs its industry peers
A metric-by-metric comparison of Upstream Bio, Inc. against SIC 2834 — valuation, growth, profitability, quality and total return, with each figure's rank within the peer group. Every value is Go-computed from SEC filings and delayed prices; ranks are sorted positions within the group only — descriptive, not advice.
| Empresa | Market cap | P/E (TTM) | P/B | P/S | Revenue growth (YoY) | Earnings growth (YoY) | EBIT margin | ROE | ROIC | Piotroski F | 1y total return | Dividend yield |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UPBEsta | $184M#8 | — | 0.7x#3 | 64.4x#7 | 20.4%#4 | -128.4%#11 | -5618.8%#7 | -52.9%#7 | — | — | -87.0%#2 | — |
| KROS | $216M#1 | — | 0.8x#5 | 0.9x#2 | 6775.0%#1 | 146.4%#1 | 27.7%#1 | 33.2%#1 | — | — | -28.2%#1 | — |
| SIGA | $210M#3 | — | 1.3x#8 | 2.2x#3 | -31.8%#5 | -60.7%#8 | 25.1%#2 | 14.1%#2 | — | — | — | 20.5%#1 |
| KRRO | $211M#2 | — | 2.0x#9 | 33.0x#6 | 181.5%#2 | -40.3%#7 | -1906.4%#6 | -113.6%#10 | -155.2%#2 | — | — | — |
| BBOT | $206M#4 | — | 0.6x#1 | — | — | -80.5%#10 | — | -41.5%#6 | — | — | — | — |
| AKBA | $198M#5 | — | 7.9x#10 | 0.8x#1 | 47.5%#3 | 92.4%#2 | 9.9%#3 | -21.2%#4 | — | — | — | — |
| RNAC | $197M#6 | — | — | 492.4x#8 | -99.0%#9 | -68.3%#9 | -35851.3%#8 | — | — | — | — | — |
| WHWK | $185M#7 | — | 1.0x#6 | 25.9x#5 | -72.5%#7 | 67.7%#3 | -1601.1%#5 | -11.3%#3 | — | — | — | — |
| INO | $182M#9 | — | 41.8x#11 | 2792.9x#9 | -70.0%#6 | 20.6%#5 | -132871.3%#9 | -1944.6%#11 | -243.9%#3 | — | — | — |
| TRDA | $180M#10 | — | 0.8x#4 | 7.1x#4 | -87.9%#8 | -319.0%#12 | -621.1%#4 | -61.6%#8 | — | — | — | — |
| SION | $176M#11 | — | 0.7x#2 | — | — | -22.0%#6 | — | -28.3%#5 | — | — | — | — |
| ALXO | $173M#12 | — | 1.3x#7 | — | — | 24.6%#4 | — | -74.7%#9 | -84.4%#1 | — | — | — |
Peer set: US filers sharing this company's SEC industry classification (SIC 2834). SIC is coarse — conglomerates and multi-segment companies map imperfectly. Values from SEC filings + delayed prices; ranks are within-group positions only. Market cap, P/E, P/B, P/S, 1y total return and dividend yield are computed from each member's latest snapshot price when the table is built (see as-of; snapshot prices can lag) — not live. Some peers are still being computed, so this table covers part of the group and ranks are within the rows shown; it fills in shortly. Esta tabla agotó el tiempo durante su construcción, por lo que cubre parte del grupo; los rangos son solo dentro de las filas mostradas y se completará en breve. Table built 2026-11-02.
Source: SEC XBRL filings + delayed prices · ranks are within-group positions · For reference only · Not investment advice