KRYSKrystal Biotech, Inc.vs its industry peers
A metric-by-metric comparison of Krystal Biotech, Inc. against SPDR S&P Biotech ETF holdings — valuation, growth, profitability, quality and total return, with each figure's rank within the peer group. Every value is Go-computed from SEC filings and delayed prices; ranks are sorted positions within the group only — descriptive, not advice.
| Company | Market cap | P/E (TTM) | P/B | P/S | Revenue growth (YoY) | Earnings growth (YoY) | EBIT margin | ROE | ROIC | Piotroski F | 1y total return | Dividend yield |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| KRYSThis | $10.0B#1 | 42.2x#1 | 7.3x#7 | 25.6x#2 | 33.9%#4 | 129.7%#1 | 41.5%#1 | 15.1%#2 | 17.2%#1 | — | 118.3%#4 | — |
| TWST | $9.0B#4 | — | 20.1x#11 | 23.8x#1 | 20.3%#5 | 62.8%#2 | -36.2%#2 | -17.4%#8 | -41.4%#3 | — | — | — |
| ORKA | $6.2B#9 | — | 5.6x#3 | — | — | -25.9%#7 | — | -9.5%#5 | — | — | 529.7%#3 | — |
| KYMR | $9.7B#2 | — | 6.4x#5 | 246.9x#5 | -16.7%#6 | 39.1%#3 | -891.1%#5 | 20.6%#1 | — | — | — | — |
| VKTX | $3.4B#12 | — | 8.4x#8 | — | — | -227.1%#13 | — | -88.1%#12 | — | — | 24.7%#7 | — |
| PRAX | $8.6B#6 | — | 6.4x#6 | — | -100.0%#8 | -65.6%#10 | — | -22.6%#10 | — | — | 634.9%#2 | — |
| ERAS | $5.4B#11 | — | 14.9x#9 | — | — | 23.0%#5 | — | -34.4%#11 | — | — | 804.7%#1 | — |
| RYTM | $6.7B#7 | — | 65.4x#12 | 35.5x#3 | 45.8%#3 | 24.6%#4 | -101.2%#3 | -0.2%#4 | -133.8%#4 | — | — | — |
| CGON | $6.6B#8 | — | 6.4x#4 | 1627.1x#6 | 254.7%#2 | -82.9%#11 | -4722.1%#6 | -15.6%#7 | -18.8%#2 | — | 107.2%#5 | — |
| SLS | $2.4B#13 | — | 17.1x#10 | — | -100.0%#8 | 13.0%#6 | — | -19.5%#9 | — | — | — | — |
| PCVX | $8.7B#5 | — | 3.2x#1 | — | — | -65.2%#9 | — | -0.0%#3 | — | — | — | — |
| DNTH | $5.7B#10 | — | 4.9x#2 | 2815.7x#7 | -67.3%#7 | -91.1%#12 | -8739.3%#7 | -13.9%#6 | — | — | — | — |
| CYTK | $9.6B#3 | — | — | 109.6x#4 | 376.6%#1 | -33.2%#8 | -695.4%#4 | — | — | — | 39.5%#6 | — |
Peer set: top holdings of XBI (SPDR S&P Biotech ETF), the indexed fund holding this stock at its highest weight — a fund manager's grouping, not Tickwind's judgement. Values from SEC filings + delayed prices; ranks are within-group positions only. Market cap, P/E, P/B, P/S, 1y total return and dividend yield are computed from each member's latest snapshot price when the table is built (see as-of; snapshot prices can lag) — not live. Some peers are still being computed, so this table covers part of the group and ranks are within the rows shown; it fills in shortly. This table timed out mid-build, so it covers part of the group; ranks are within the rows shown and it fills in shortly. Table built 2026-09-16.
Source: SEC XBRL filings + delayed prices · ranks are within-group positions · For reference only · Not investment advice